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Network Member Profile

Current Field of Study

• Investigations of the functions of genes and proteins in a range of cattle and sheep production traits.
• Identification of genes and proteins associated with mastitis resistance in dairy cows and genes linked with marbling in beef cattle
• Identification of the functions of imprinted genes and non-coding genes in myogenesis and adipogenesis (Dlk-1 locus) particularly during development
• The Bovine Genome Sequencing Project

Australian Collaborators

• Dr Caroline McMillen, Physiology, The University of Adelaide, Adelaide, South Australia
• Dr Matt McDonagh, Department of Primary Industries, Werribee, Victoria
• Dr Stuart Smith, Deakin University
• Dr jason White, Melbourne University
• CSIRO Epigenetics Initiative

International Collaborators

• International Bovine Genome Project Consortium
• Dr Noelle Cockett, Utah State University
• Dr Chris Bidwell, Purdue University

Facilities

• Proteomics (Maldi; MS/MS; Q-TOF; TOF-TOF; 2d SDS-PAGE)
• CDNA and oligo microarray facilities (construction, printing, running and analysis)
• Livestock Bioinformatics
• Large animal facilities (via CSIRO Armidale and Rockhampton)

Recent Publications

Wong F., Tellam RL. (2007) A microRNA targeting Enhancer of Zeste promotes myogenesis. (submitted).

White, J., Vuocolo, T., McDonagh, M., Grounds, M., Harper, G., Cockett, N., Tellam, R. (2007) Analysis of the callipyge phenotype through skeletal muscle development; association of Dlk1 with muscle precursor cells. Differentiation, August 2007(in print).

Fleming-Waddell JN, Wilson LM, Olbricht GR, Vuocolo T, Byrne K, Craig BA, Tellam RL, Cockett NE, Bidwell CA. (2007) Analysis of gene expression during the onset of muscle hypertrophy in callipyge lambs. Animal Genetics 38:28-36.

Vuocolo T, Byrne K, White J, McWilliam S, Reverter A, Cockett NE, Tellam RL. Identification of a gene network contributing to hypertrophy in callipyge skeletal muscle. (2007) Physiological Genomics. 28:253-72.

Leeton L. and Tellam R.L. (2007) Over-expression of Rtl1 has No Effect on Adipogenesis. Funct Integr Genomics. 2007 7:257-61.

Tellam, R. L. (2007) Capturing benefits from the bovine genome sequence. Austr. J. Exp. Agric. 47, 1039-1050.

Tellam, R. (2007) The Impact of Genomics on Livestock Production. In Redesigning Animal Agriculture. (CABI Publishing).

Snelling, W. M., Chiu, R., Schein, E., Hobbs, M., Abbey, C. A., Adelson, D. L., Bosdet, I. E., Brauning, R., Caetano, AR, Costa, MM, Crawford, A.M., Dalrymple, B., Eggan, A., Everts-van der wind, A., Gill, C., Green, R.D., Holt, R., Jones, S.J.M., Kappes, S.M., Keele, J.W., De Jong, P.J., Krzywinski, M., Larkin, D.M., Lewin, H.A., McEwan, J.C., Marra, M.A., Mathewson, C.A., Matukumalli, L.K., Moore, S.S., Osoegawa, K., Skow, L.C., Sonstegard, T.S. Tellam, R.L., Van Tasell, C.P., Williams, J.L., Womack, J.E., Wye, N.H., Yang, G., Zhao, S. (2007) A physical map of the bovine genome. Genome Biology 8, R165.

Vuocolo, T., Byrne, K., McWilliam, S., Reverter, T., Cockett, N.E. and Tellam, R.L. (2006) Identification of a gene network contributing to muscle hypertrophy in callipyge skeletal muscle. Physiological Genomics (in press).

Vuocolo, T., Cockett, N., Tellam, R. L. (2005) Expression of imprinted genes surrounding the callipyge mutation in ovine skeletal muscle. Australian Journal of Experimental Agriculture 45, 879-892

Strandberg, Y., Gray, C., Vuocolo, T., Donaldson, L. and Tellam, R. L. (2005) Lipopolysaccharide and lipoteichoic acid induce different innate immune responses in bovine mammary epithelial cells. Cytokine 31, 72-86.

Christian Gray, Ylva Strandberg, Laurelea Donaldson and Ross Tellam (2005) Bovine Mammary Epithelial Cells, Initiators of Innate Immune
Responses to Mastitis: a Review. Australian Journal of Experimental Agriculture 45, 757-761.

Vuocolo, T., Cockett, N., Tellam, R. L. (2005) Expression of imprinted genes surrounding the callipyge mutation in ovine skeletal muscle.
Australian Journal of Experimental Agriculture 45, 879-892.

Donaldson, L., Vuocolo, T., Strandberg, Y., Gray, C., Wang, Y.-K. and R. L. Tellam (2005) Construction and validation of a bovine innate immune microarray. BMC Genomics 6, 135.

Celi P, Martin GB, Blache D, Vercoe PE, Blackberry M, Tellam RL. (2003) Effect of food deprivation on blood concentration of metabolic hormones in Merino rams: the role of leptin. Vet Res Commun. 2003 Sep;27 Suppl 1:219-20.

Vuocolo, T., Pearson, R., Campbell, P. and Tellam, R. L. (2003) Differential expression of Dlk-1 in bovine adipose tissue depots. Comparative Biochemistry and Physiology B 134, 315-333.

Tellam, R. L., Vuocolo, T., Eisemann, C., Briscoe, S., Riding, G., Elvin, C. and Pearson, R. (2002) Identification of an immuno-protective mucin-like protein, peritrophin-55, from the peritrophic matrix of Lucilia cuprina larvae. Insect Biochemistry and Molecular Biology 33, 239-252.

Tellam, J., Sherritt, M., Thomson, S., Tellam, R., Moss, D., Burrows, S., Wiertz, E. and Khanna, R. (2001) Targeting of EBNA1 for rapid intracellular degradation overrides the inhibitory effects of the Gly-Ala repeat domain and restores CD8+ T cell recognition. Journal of Biological Chemistry 276, 33353-33360.

Wijjfels, G., Eisemann, C., Riding, G., Pearson, R., Jones, A., Tellam, R.L. (2001) A novel family of chitin binding proteins from insect type II peritrophic matrix:cDNA sequences, chitin binding activity and cellular localization. Journal of Biological Chemistry 276, 15527-15536.

Tellam, R. L., Vuocolo, T., Johnson, S., Jarmey, J., Pearson, R. (2000) Insect chitin synthase: cDNA sequence, gene organization and expression. European Journal for Biochemistry 267, 6025-6043.

Kauter, K. G.; Ball, M.; Tellam, R. L., and McFarlane, J. R. (2000) Adrenaline, insulin and glucagon do not have acute effects on plasma leptin levels in sheep: development and characterization of an ovine leptin ELISA. J. Endocrinology 166, 127-135

Blache, D., Tellam, R. L., Chagas, L. M., Blackberry, M. A., Vercoe, P. E. and Martin, G. B. (2000) Level of nutrition affects leptin concentrations in plasma and cerebrospinal fluid in sheep. J. Endocrinology 165, 625-637.