Network Member Profile
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Professor Peter Rathjen
Organisations:
University of Melbourne, Melbourne
VIC 3010
Dean Faculty of Science
Department of Zoology
Telephone: 03 8344 6407 Facsimile: 03 8344 6293
University of Adelaide, Adelaide SA
5005
Honorary Visiting Professor
Faculty of Sciences, School of Molecular and Biomedical Science (Biochemistry),
ARC Special Research Centre for the Molecular Genetics of Development
and
Australian Stem Cell Centre
Telephone: 08 8303 4671 Facsimile: 08 8303 5338
Email: prathjen@unimelb.edu.au
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Current Field of Study
- Early mammalian development
- Development of cell therapeutics for the treatment of human disease
Australian Collaborators
- Professor John Hopwood, Women's and Children's Hospital, Adelaide
International Collaborators
- Dr David Gilbert, J Herbert Taylor Professor of Biological Science, Florida
State University, FL, USA
Facilities
- Microarray and proteomics centre
- Centre for Electron Microscopy and Microstructure Analysis
- Laser-dissection microscope
- Human and Mouse stem cell culture facilities
- Mouse transgenics facility
- Antibody production facility
Lab Members
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Prof Peter Rathjen
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Head of the Lab
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Melbourne University
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Dr Joy Rathjen
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Senior Research Fellow
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Melbourne University
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Dr Rebecca Keough
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Senior Research Fellow
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Head of the Adelaide University Laboratory
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| Ms Lynda Gregory-Badger |
Business Manager |
Adelaide University |
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Dr Norihisa Shindo
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Postdoctoral Fellow
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Adelaide University |
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Mr James Hughes
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PhD Student
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Adelaide University |
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Miss Tiffany Liu
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PhD Student
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Adelaide University |
| Ms Sarah To |
PhD Student
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Adelaide University |
Recent Grant Income
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Description
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CIs
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Type of Grant
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Year
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Income p.a.
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| Cell Differentiation |
Rathjen, PD |
ARC Special Research Centre for Molecular Genetics of Development |
2000-2008 |
$100,000 |
| Embryonic Stem Cell - Characterisation |
Rathjen, PD, Morris, MB, Rathjen, J
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Australian Stem Cell Centre |
2004-2006 |
$428,000 |
| Immune Modulation - Reprogramming 2 |
Rathjen, PD, Morris, MB, Rathjen, J |
Australian Stem Cell Centre |
2004-2006 |
$221,000 |
Recent Publications
Johnson, B.V., Rathjen, J., and Rathjen P.D. (2006) Transcriptional control
of pluripotency: decisions in early development, Current Opinion in Genetics
& Development 16:447-454
Pralong, D., Lim, M.L., Vassiliev, I., Mrozik, K., Wijesundara, N., Rathjen
P.D., and Verma, P.J. (2005) Tetraploid embryonic stem cells contribute to the
inner cell mass of mouse blastocysts. Cloning and Stem Cells Volume 7, Number
4 2005, 272-278
Kavanagh, S.J., Schulz, T.C., Davey, P., Claudianos, C., Russell, C., and Rathjen,
P.D. (2005) A family of RS domain proteins with novel subcellular localisation
and trafficking. Nucleic Acids Research 33, 1309-22
Lang, K.J., Rathjen, J., Vassilieva, S., Rathjen, P.D. (2004) Differentiation
of embryonic stem cells to a neural fate: a route to rebuilding the nervous
system. Journal of Neuroscience Research 76: 184-92
Rathjen, J., Washington, J.M., Bettess, M.D., Rathjen, P.D. (2003) Identification
of a biological activity that supports maintenance and proliferation of pluripotent
cells from the primitive ectoderm of the mouse. Biology of Reproduction 69:
1863-71
Pelton, T.A., Sharma, S., Schultz, T.C., Rathjen, J., Rathjen, P.D. (2002) Transient
pluripotent cell populations during primitive ectoderm formation: Correlation
of in vivo and in vitro pluripotent cell development. Journal of Cell Science
115:329-39
Rathjen, J., Haines, B.P., Hudson, K., Nesci, A., Dunn, S., Rathjen, P.D., (2002)
Directed differentiation of pluripotent cells to neural lineages: homogenous
formation and differentiation of a neurectoderm population. Development 129:2649-61
Rodda, S.J., Kavanagh, S.J., Rathjen, J., Rathjen P.D. (2002) Embryonic stem
cell differentiation and the analysis of mammalian development. International
Journal of Developmental Biology 46:449-58
Stead, E., White, J., Faast, R., Conn, S., Goldstone, S., Rathjen, J., Dhingra,
U., Rathjen, P., Walker D., Dalton, S. (2002) Pluripotent cell division cycles
are driven by ectopic Cdk2, cyclin A/E and activities. Oncogene 21: 8320-33
Faast, R., Thonglairoam, V., Schulz, T.C., Beall, J., Wells, J.R., Taylor, H.,
Matthaei, K., Rathjen, P.D., Tremethick, D.J., Lyons, I. (2001) Histone variant
H2A.Z is required for early mammalian development. Current Biology. 11:1183-7.
Rodda, S., Sharma, S., Scherer, M., Chapman, G., Rathjen, P.D. (2001) CRTR-1,
a developmentally regulated transcriptional repressor related to the CP2 family
of transcription factors. Journal of Biological Chemistry 276:3324-32. Epub
2000 Nov 9.
Rathjen, J., Rathjen, P.D. (2001) Mouse ES cells: experimental exploitation
of pluripotent differentiation potential. Current Opinion in Genetics of Development.
11:587-94.
BOOKS
Morris, M.B., Rathjen, J., Keough, R.A., Rathjen, P.D. (2005) Biology of embryonic
stem cells. In Human Embryonic Stem Cells, pages 1-28, edited by J.S. Odorico,
R.A. Pederson and S.C. Zhang, BIOS Scientific
Rathjen, J., Rathjen, P.D. (2004) Embryonic Stem Cells. Isolation and application
of pluripotent cells from pregastrulation mammalian embryo in Stem Cell Handbook
p.33-43, edited by S. Sell, Humana Press Inc., Totowa, N.J., USA.
Rathjen, J., Rathjen, P.D. (2003) Lineage specific differentiation of mouse
ES cells: formation and differentiation of early primitive ectoderm-like (EPL)
cells. In Methods in Enzymology, Vol 365: Differentiation of embryonic stem
cells pages 3-25, edited by J.N. Abelson and M.I. Simon, Elsevier Academic Press
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