Network Member Profile
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Dr Tim JM Moss
Department:
Department of Physiology
Organisation:
Monash University
Address:
Building 13F, Victoria, Australia 3800
Telephone: 03 9905 5233 Facsimile: 03
9905 2547
Email: tim.moss@med.monash.edu.au
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Current Field of Study
- Fetal developmental effects of antenatal corticosteroids and intrauterine
inflammation
Australian Collaborators
- Prof Harding, Richard (Monash University, Clayton, VIC)
- Assoc Prof Rees, Sandra (University of Melbourne, Melbourne, VIC)
- A/Prof Stuart Hooper (Monash University, Clayton, VIC)
- Dr Claire Roberts (Adelaide University, Adelaide, SA)
- Prof John Newnham (UWA)
- Dr Ilias Nitsos (UWA)
- Dr Graeme Polglase (UWA)
- Dr Jane Pillow (UWA)
International Collaborators
- Prof Alan Jobe (Children's Hospital Research Foundation, Cincinnati, USA)
- Prof John Challis (University of Toronto, Canada)
- Dr Suhas Kallapur (Cincinnati Children's Hospital, Cincinnati, USA)
- Dr Boris Kramer (Mastrict, Germany)
Recent Grant Income
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Description
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CIs
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Type of Grant
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Year
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Income p.a.
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RD Wright Biomedical Career Development Award
(ID 303261)
Suspended October 2006 - October 2007
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TJM Moss |
National Health and Medical Research Council, Australia
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2004-2009 |
$417,500 total |
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Intrauterine ureaplasma infection during pregnancy: fetal effects and
characteristics of ureaplasma pathogenicity
Status as CIA changed to CIE
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TJM Moss, CL Knox, I Nitsos, AH Jobe, JP Newnham |
National Health and Medical Research Council, Australia |
2007-2009 |
$507,750 total |
| Neonatal Resuscitation and Preterm Lung Injury |
AH Jobe, TJM Moss |
National Institutes of Health, USA |
2006 |
Australian component $US 283,829 total |
| Postnatal consequences of fetal inflammation |
AH Jobe, S Kallapur, BW Kramer, JJ Pillow, GR Polglase, TJM
Moss |
National Institutes of Health, USA |
2006 |
Australian component $US 140,000 total |
| New Mediators of Clinical Lung Maturation. |
AH Jobe (Principal investigator), Machiko Ikegami, Cindy
Bachurski, Suhas Kallapur
TJM Moss (Australian Principal Investigator)
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National Institutes of Health, USA
Consortium grant
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2004-2006 |
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Recent Publications
Kallapur, S.G., I. Nitsos, T.J.M. Moss, B.W. Kramer, J.P. Newnham, M. Ikegami
& A.H. Jobe. Chronic endotoxin exposure does not cause sustained structural
abnormalities in the fetal sheep lungs. American Journal of Physiology Lung
Cellular and Molecular Physiology 288:L966-L974, 2005.
Moss, T.J.M., D.A. Doherty, I. Nitsos, D.M. Sloboda, R. Harding & J.P. Newnham.
Effects into adulthood of single or repeated antenatal corticosteroids in sheep.
American Journal of Obstetrics and Gynecology 192:146-152, 2005.
Moss, T.J.M., I. Nitsos, M. Ikegami, A.H. Jobe & J.P. Newnham. Experimental
intrauterine Ureaplasma infection in sheep. American Journal of Obstetrics and
Gynecology 192:1179-1186, 2005
Kramer B.W., M. Ikegami, T.J.M. Moss, I. Nitsos, J.P. Newnham, AH Jobe. Endotoxin-induced
chorioamnionitis modulates innate immunity of monocytes in preterm sheep. American
Journal of Respiratory and Critical Care Medicine.171:73-77, 2005.
Mulrooney, N. Z. Champion, T.J.M. Moss, I. Nitsos, M. Ikegami & A.H. Jobe.
Surfactant and Physiological Responses of Preterm Lambs to Continuous Positive
Airway Pressure. Submitted to American Journal of Respiratory and Critical Care
Medicine 171:488-493, 2005.
Newnham, J.P., A. Shub, A.H. Jobe, P.S. Bird, M. Ikegami, I. Nitsos & T.J.M.
Moss. The effects of intra-amniotic administration of periodontal lipopolysaccharides
in sheep. American Journal of Obstetrics and Gynecology 193:313-21, 2005
Kallapur, S.G., T.J. Moss, M. Ikegami, R.L. Jasman, J.P. Newnham & A.H.
Jobe. Recruited inflammatory cells mediate endotoxin induced lung maturation
in preterm fetal lambs. American Journal of Respiratory and Critical Care Medicine
172: 1315-1321, 2005.
Sloboda, D.M., J.R.G. Challis, T.J.M. Moss & J.P. Newnham. Synthetic glucocorticoids:
antenatal administration and long-term implications. Current Pharmaceutical
Design 11:1459-1472, 2005.
Sloboda, D.M., T.J.M. Moss, S. Li, D.A. Doherty, I. Nitsos, J.R.G. Challis &
J.P. Newnham. Hepatic glucose regulation and metabolism in adult sheep: effects
of prenatal betamethasone. American Journal of Physiology Endocrinology and
Metabolism 289:E721-E728, 2005.
Moss, T.J.M. The respiratory consequences of preterm birth. Clinical and Experimental
Pharmacology and Physiology 33:280-284, 2006.
Nitsos, I., J. Duncan, B.W. Kramer, S. Rees, R. Harding, J.P. Newnham &
T.J.M. Moss. Neurodevelopmental effects of chronic intrauterine inflammation
in fetal sheep. Journal of The Society of Gynecologic Investigation 13:239-247,
2006.
Samnakay, N., J. Orford, A. Barker, A. Charles, P. Terry, J. Newnham & T.
Moss. Timing of morphogenic and apoptotic changes in the sheep fetal kidney
in response to bladder outflow obstruction. J Pediatr Urol 2:216-224, 2006.
Sosenko, I.R., S.G. Kallapur, I. Nitsos, T.J.M. Moss, J.P. Newnham, M. Ikegami
& A.H. Jobe. IL-1 causes lung inflammation and maturation by direct effects
on preterm fetal lamb lungs. Pediatric Research 60:294-298, 2006.
Sloboda, D.M., T.J.M. Moss, S. Li, D.A. Doherty, I. Nitsos, J.R.G. Challis &
J.P. Newnham. Prenatal betamethasone exposure results in pituitary-adrenal hypo-responsiveness
in adult sheep. American Journal of Physiology Endocrinology and Metabolism
292:E61-E70, 2007.
Polglase, G.R., I. Nitsos, A.H. Jobe, J.P. Newnham & T.J.M Moss. Maternal
and intra-amniotic corticosteroid effects on lung morphometry in preterm lambs.
Pediatric Research 6232-36, 2007.
Pillow, J.J., N. Hillman, T.J.M. Moss, G. R. Polglase, G. Bold, C. Beaumont,
M. Ikegami & A.H. Jobe. Bubble continuous positive airway pressure enhances
lung volume and gas exchange in preterm lambs. American Journal of Respiratory
and Critical Care Medicine 176;63-69, 2007.
Kramer, B.W., S.N. Joshi, T.J.M. Moss, J.P. Newnham, R. Sindelar, A.H. Jobe
& S.G. Kallapur. Endotoxin-induced maturation of monocytes in preterm fetal
sheep lung. American Journal of Physiology Lung Cellular and Molecular Physiology
293:L345-L353, 2007.
Braun, T., S. Li, T.J.M. Moss, J.P. Newnham, J.R.G. Challis, P.D. Gluckman &
D.M. Sloboda. Maternal betamethasone administration reduces binucleate cell
number and ovine placental lactogen in sheep. Journal of Endocrinology 194:337-347,
2007.
Hillman, N., T.J.M. Moss, S.G. Kallapur, C. Bachurski, J.J. Pillow, G.R. Polglase,
I. Nitsos, B.W. Kramer & A.H. Jobe. Brief, large tidal volume ventilation
initiates lung injury and a systemic response in fetal sheep. American Journal
of Respiratory and Critical Care Medicine 176:575-581, 2007.
Jobe, A.H. T.J.M. Moss, I. Nitsos, M. Ikegami, S.G. Kallapur & J.P. Newnham.
Betamethasone for lung maturation: testing doses and formulation in fetal sheep.
American Journal of Obstetrics and Gynecology 197:523.e1-523.e6, 2007.
Moss, T.J.M., C.L. Knox, S.G. Kallapur, I. Nitsos, C. Theodoropoulos, M. Ikegami,
J.P. Newnham & A.H. Jobe. Experimental amniotic fluid infection in sheep:
effects of Ureaplasma parvum serovars 3 and 6 on preterm or term fetal sheep.
American Journal of Obstetrics and Gynecology (In press).
Kallapur, S.G. A.H. Jobe, M.K. Ball, I. Nitsos, T.J.M. Moss, N. Hillman, J.P.
Newnham & B.W. Kramer. Pulmonary and systemic endotoxin tolerance in preterm
fetal sheep exposed to chorioamnionitis. Journal of Immunology (In press).
Hillman, N., T.J.M. Moss, I. Nitsos, B.W. Kramer, C. Bachurski, M. Ikegami,
A.H. Jobe & S.G. Kallapur. Toll-like receptors and agonist responses in
the developing fetal sheep lung. American Journal of Physiology Lung Cellular
and Molecular Physiology (In press).
Burrage, D., L.R. Green, T.J.M. Moss, I. Nitsos, J.P. Newnham & M.A. Hanson.
The role of the carotid body in fetal growth responses to moderate maternal
undernutrition in late gestation sheep. British Journal of Obstetrics and Gynecology
(In press).
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