Network Member Profile
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Dr Adam Hart
Department:
Anatomy and Developmental Biology
Organisation:
Monash University
Address:
Wellington Road, Clayton, VIC, 3800
Telephone: 03 9905 2761, Facsimile: 03
9905 2462
Email: adam.hart@med.monash.edu.au
Web
Address
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Current Field of Study
Australian Collaborators
- Dr Lorraine Robb (Walter and Eliza Hall Institute, Melbourne, Victoria)
- Dr Jane Visvader (Walter and Eliza Hall Institute, Melbourne, Victoria)
- Dr Orly Lacham-Kaplan (Monash Immunology and Stem Cell Laboratories, Melbourne,
Victoria)
- Professor John Bertram (Monash University, Anatomy and Developmental Biology
Department, Melbourne, Victoria)
International Collaborators
- Associate Professor Leendert Looijenga (Erasmus Medical School, Rotterdam,
Netherlands)
Facilities
- Australian Synchrotron
- Monash Antibody Technologies Facility
- Optical Dissector for Stereological Analysis
- Optical Projection Tomography
Lab Members
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Dr Adam Hart
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Head of the Lab
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Mr Ismael Aguirre-Maclennan
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Masters Student
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Recent Grant Income
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Description
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CIs
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Type of Grant
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Year
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Income p.a.
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| Regulation Of Self-Renewal and Pluripotency in
Embryonic and Germline Stem Cells |
A Hart |
NHMRC Project Grant |
2006-2008 |
$168,000 |
| Molecular Regulation of Blood Cell
Production and Function |
N Nicola, D Metcalf, D Hilton, L
Robb, A Roberts, W Alexander, R Starr, R Norton, Co-I: A Hart
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NHMRC Program Grant |
2007-2011 |
$3,400,000 |
Recent Publications
Stefan Glaser, Donald Metcalf, Li Wu, Adam H. Hart, Ladina DiRago, Sandra Mifsud,
Angela D'Amico, Samantha Dagger, Chiara Campo, Angela C. Chan David J Izon,
Lorraine Robb. "Enforced expression of the homeobox gene Mixl1 impairs
hematopoietic differentiation and results in acute myeloid leukemia." (2006)
P.N.A.S. Oct 31;103(44):16460-5.
Forrai, A., Boyle, K., Hart, A.H., Hartley, L., Rakar, S., Willson, T.A., Simpson,
K.M., Roberts, A.W, Alexander W.S., Voss, A.K., and Robb, L. "SOCS3 regulates
the balance between self-renewal and differentiation in murine embryonic stem
cells." (2005) Stem Cells Mar;24(3):604-14.
Hart, A.H., Hartley, L., Parker, K., Ibrahim, M., Looijenga, L.H.J., Pauchnik,
M., Chow, C-W., & Robb, L. The Pluripotency Homeobox Gene NANOG is expressed
in Human Germ Cell Tumours. (2005) CANCER. 104(10). 2092-2098
Hart, A. H., Willson, T. A., Wong, M., Parker, K. & Robb, L. Transcriptional
regulation of the homeobox gene Mixl1 by TGF-_ and FoxH1. (2005) Biochemical
and Biophysical Research Communications, 333. 1361-1369
Hart AH, Hartley L, Ibrahim M, Robb L. Identification, cloning and expression
analysis of the pluripotency promoting NANOG genes in mouse and human. (2004)
Developmental Dynamics. May;230(1):187-98.
Hart AH, Hartley L, Sourris K, Stadler ES, Li R, Stanley EG, Tam PP, Elefanty
AG, Robb L. Mixl1 is required for axial mesendoderm morphogenesis and patterning
in the murine embryo. (2003) Development. Aug;129(15):3597-608.
Yuki Kimura, Adam Hart, Masanori Hirashima, Chen Wang, Doug Holmyard, Jackie
Pittman, Xin-li Pang, Carl Jackson and Alan Bernstein. Hzf-Deficiency causes
abnormal ?-granule formation in megakaryocytes and defective homeostasis in
vivo. (2003) J Exp Med. Apr 1;195(7):941-52.
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