Network Member Profile (Overseas Affiliate)
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Dr Catherine L Coulter
Department:
Department of Pediatrics, Division of Neonatalogy
Organisation:
University of Washington
Address:
BOX 356320, Seattle, WA 98195. Telephone: +1 206 543 4827 Facsimile:
+1 206 543 8626
Email:
ccoulter@u.washington.edu
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Current Field of Study
My research focuses on the factors that regulate the synthesis and section
of glucocorticoids and the role of the glucocorticoids in prenatal programming
of the key endocrine systems which regulate blood pressure (the renin-angiotensin
systems in the adrenal, kidney and fetal vasculature) and glucose homeostasis
(insulin-axis, and its major targets, the liver kidney and skeletal muscle)
postnatally, which are implicated in the fetal origins of adult disease.
Australian Collaborators
- Associate Professor Paul Greenwood, NSW Department of Primary Industries
International Collaborators
- Associate Professor Ian Bird, Dept Obstetrics and Gynecology, University
of Wisconsin, Madison, Wisconsin, USA
- Associate Professor Alice Tarantal, Californian Regional Primate Research
Center, University of California, Davis, California, USA.
- Professor Richard Pestell, Director, Lombardi Comprehensive Cancer Center,
Chairman Department of Oncology, Georgetown University, Washington, DC, USA
- Professor Robert B. Jaffe, Reproductive Endocrinology Center, University
of California, San Francisco, CA, USA.
- Dr Hugh Bennett, Sheldon Biotechnology Centre McGill University Montreal,
Quebec, Canada.
Recent Grant Income
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Description
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CIs
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Type of Grant
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Year
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Income p.a.
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| The Early Origins of Adult Disease |
JS Robinson, IC McMillen, JA Owens, J Schwartz, CL Coulter
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NHMRC Program Grant |
2002-2006 |
$915,000 |
| R.Douglas Wright Biomedical Career Development Award |
CL Coulter |
NHMRC |
2002-2006 |
$83,000 |
Recent Publications
Coulter CL 2005. Regulation of fetal adrenal development. Trends in Endo Metab.
Coulter pub list#22 In Press
McMillen IC, Schwartz J, Coulter CL, Edwards LJ. (2004) Early embryonic environment,
the fetal pituitary-adrenal axis and the timing of parturition. Endocr Res.
2004 Nov;30(4):845-50.
Warnes KE, McMillen IC, Robinson JS, Coulter CL. (2004) Metyrapone infusion
stimulates adrenal growth without activating the cell cycle or the IGF system
in the late gestation fetal sheep. Endocr Res. 2004 Nov;30(4):535-9.
Coulter CL. (2004) Functional biology of the primate fetal adrenal gland:
advances in technology provide new insight. Clin Exp Pharmacol Physiol. 2004
Aug;31(8):475-84. Review.
Warnes KE, McMillen IC, Robinson JS, Coulter CL. (2004) Differential actions
of metyrapone on the fetal pituitary-adrenal axis in the sheep fetus in late
gestation. Biol Reprod. 2004 Aug;71(2):620-8.
Williams SJ, Olson DM, Zaragoza DB, Coulter CL, Butler TG, Ross JT, McMillen
IC. (2004) Cortisol infusion decreases renin, but not PGHS-2, EP2, or EP4 mRNA
expression in the kidney of the fetal sheep at days 109-116. Pediatr Res. 2004
Apr;55(4):637-44.
C.L. Coulter, M.D. Salkeld and I.C. McMillen (2003). Adrenal TGF b 1 mRNA
levels fall during late gestation and are not regulated by cortisol in the sheep
fetus. Molecular and Cellular Endocrinology 206: 85-91.
C.L. Coulter, J.T. Ross, J.A. Owens, H.P.J. Bennett and I.C. McMillen (2002)
Role of pituitary POMC-peptides and growth factors in the developmental biology
of the adrenal gland. Archives in Physiology and Biochemistry. 110:99-105
C.L. Coulter, I. C. McMillen, I. M. Bird and M. D. Salkeld (2002) Steroidogenic
Acute Regulatory Protein (StAR) expression is decreased in the Adrenal Gland
of the Growth Restricted Sheep Fetus during Late Gestation. Biology of Reproduction
67: 584-590
C. L. Coulter, L.C. Read, S. Barry A. F. Tarantal, and D.M. Styne (2001). Mechanism
of action of exogenous EGF administration in stimulating the morphological and
functional maturation of the adrenal gland of the fetal rhesus monkey in
vivo. Pediatric Research 50: 210-216.
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