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Network Member Profile

Current Field of Study

• Endocrine regulation of respiratory development

Australian Collaborators

• A/Prof Stuart Hooper, Monash University, Melbourne, Victoria
• Prof Richard Harding, Monash University, Melbourne, Victoria
• Prof. Colin Morley, Royal Women's Hospital, Melbourne, Victoria
• A/Prof Peter Davis, Royal Women's Hospital, Melbourne, Victoria
• Prof. Margaret Morris, UNSW, Sydney, NSW
• Prof Dale Godfrey, Uni. of Melbourne, Melbourne, Victoria
• Prof. Brendan Waddell, UWA, Perth, WA.
  

International Collaborators

• Prof. Wen Xie, University of Pittsburgh, Pittsburgh, PA, USA
• Prof David Pearce, UCSF, San Francisco, CA, USA
• Dr. Isabelle Hoong, Massey University, Auckland, NZ
  

Recent Publications

Gong H., Jarzynka M., Cole T.J., Lee JH, Dr. Wada T., Zhang B, Gao J., Song W-C., DeFranco D., Cheng S-Y., Xie W. (2008) Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase. Cancer Res. (in press).

Velkoska E., Cole T.J., Dean R.G., Burrell L.M. Morris MJ (2008) Acute and chronic effects of early nutritional changes on adiposity and cardiac fibrosis J. Nutrition (in press).

Denham M., Conley B.J., Olsson F., Gulluyan L., Cole T.J., Mollard R. (2007) A Murine Respiratory inducing niche displays variable efficiency across human and mouse embryonic stem cell species. Am. J. Physiol. Lung Cell Mol. Physiol. 292(5):L1241-7.

Wong S., Brennan F.E., Young M.J., Fuller, P.J. and Cole T.J. (2007) A Direct Effect of Aldosterone on Endothelin-1 Gene Expression in vivo. Endocrinology 148(4):1511-7.

Bird A.D., Tan K.H., Olsson P.F., Zieba M., Flecknoe S.J., Liddicoat D.R., Mollard R., Hooper S.B., Cole T.J. (2007) Identification of glucocorticoid-regulated genes that control cell proliferation during respiratory development. J. Physiol. 585(Pt 1):187-201.

Cole T.J. and Mollard R. (2007) Selective Glucocorticoid Receptor Ligands Medicinal Chemistry 585(Pt 1):187-201.

Olsson F., Denham M., Cole T.J., Hooper S.B., Mollard R. (2007) Deriving Respiratory Cell Types from Stem Cells. Current Stem Cell Research and Therapy 2(3):197-208.

Anakk S., Huang W., Staudinger J.L., Tan K., Cole T.J., Moore D.D., and Strobel H.W. (2007) Gender dictates the nuclear receptor-mediated regulation of CYP3A44. Drug Metab Dispos. Jan;35(1):36-42.

Denham M., Cole T.J. and Mollard R. (2006) Embryonic stem cells form glandular structures and express surfactant protein-C following culture with dissociated fetal respiratory tissue Am. J. Physiol. Lung Mol. Cell Biol. 290: L1210-1215.

Cole. T.J. (2006) Glucocorticoid actions and the development of selective glucocorticoid receptor modulators. Biotech. Ann. Rev. 12, 269-300.

Velkoska E., Cole T.J., Morris M.J. (2005). Early dietary intervention: long term effects of blood pressure, brain neuropeptide Y and adiposity markers. Am. J. Physiol. Endo. Metab. (in press, accepted Jan12). (IF 3.3)

Denham M., Conley B., Young J., Olsson F, Cole T.J. and Mollard R. (2005) A stem cell overview Current Protocols in Cell Biology Ch. 23:Unit 23.1

Cole T.J., Liddicoat D.R. and Godfrey D.I. (2005). Intrathymic Glucocorticoid Production and Thymocyte Survival: Another Piece in the Puzzle Endocrinology 146, 2499-2500.

Conley B., Denham M., Gulluyan L., Olsson F, Cole T.J. and Mollard R. (2005) Mouse Embryonic Stem Cell Derivation and Mouse and Human Embryonic Stem Cell Culture and Differentiation. Current Protocols in Cell Biology Ch. 23:Unit 23.2.

Morris M.J., Velkoska E., Cole T.J. (2005) Central and peripheral contributions to obesity-associated hypertension: impact of early overnourishment Exp. Physiol. 90.5, 697-702.

Cole T.J., Solomon N.M., Van Driel R., Monk J.A., Bird D, Richardson S.J., Dilley R., Hooper S.B. (2004) Altered epithelial cell proportions in the fetal lung of glucocorticoid receptor null mice. Am J Resp Cell Mol Biol 30: 613-619. (CI 1, IF 4.0)

Medley T.L., Cole T.J., Dart A.M., Gatzka C.D., Kingwell B.A. (2004). Matrix metalloproteinase9 genotype influences large artery stiffness through effects on aortic gene and protein expression. Arterioscler Thromb Vasc Biol. 24(8), 1479-1484. (CI 1, IF 5.8)

Purton J.F., Monk J.A., Liddicoat D.R., Kyparissoudis K., Sakkal S., Richardson S.J., Godfrey D.I., Cole T.J. (2004). Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death. J. Immunol. 173, 3816-3824. (IF 7.1)

Zhan Y, Funda DP, Every AL, Fundova P, Purton JF, Liddicoat DR, Cole TJ, Godfrey DI, Brady JL, Mannering SI, Harrison LC, Lew AM. (2004). TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death Int Immunol. 16(9), 1315-1321. (IF 3.6)

Cole T. J., Pearce D. (2003) Aldosterone: Its receptor, target genes and actions. Vitamins Hormones 66, 29-76. (CI 6, IF 3.4).

Zhan Y., Purton J.F., Godfrey D.I., Cole T.J., Carbone F.R., Heath W.R., Lew A.M. (2003), Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation. P Natl Acad Sci USA. 100, 1197-1202. (CI 5, IF 10.3)

Medley T.L.,, Kingwell B.A., Gatzka C. D., Dart A.M., Cole T.J. (2003) Genetic variation in the human stromelysin-1 promoter affects age but not coronary disease related aortic stiffening. Circ Res 92, 1254-1261 (CI 7, IF 10.1)